Since 2006, Mali Health has advanced sustainable improvements in health care quality and access for people living in impoverished areas of Bamako. The organization began in Sikoro, a peri-urban slum, as a partnership between Brown University students, local government leaders, Commune-level health officials, local residents, and grassroots donors. Over the past seven years, Mali Health has instituted several programs that focus on improving maternal and child health outcomes amongst Bamako’s most impoverished populations. Mali Health delivers cost-effective results through community-driven, culturally appropriate, and sustainable approaches and serves as an effective development model for other communities.