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A fundamental knowledge gap pertains to the barriers hindering SME development in low- and middle-income countries. Slow SME growth is often attributed to a number of perceived constraints, but little research rigorously tests how those constraints affect SMEs’ ability to invest, create jobs, and grow. For example, how important is the lack of managerial human capital for firm profits and employment generation? Is access to credit a binding constraint for SMEs, or are other financial services more critical for supporting SME growth? A better understanding of which barriers affect SME development, and why, is critical for informing SME-related policies and interventions.